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Target
Mu-type opioid receptor
Ligand
BDBM50210234
Substrate
n/a
Meas. Tech.
ChEMBL_443967 (CHEMBL892114)
Ki
198±n/a nM
Citation
 Ho, GD; Bercovici, A; Tulshian, D; Greenlee, WJ; Fawzi, A; Fernandez, X; McLeod, RL; Smith Torhan, A; Zhang, H Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 2. Bioorg Med Chem Lett 17:3028-33 (2007) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50210234
Synonyms:
1-(2-(1-(bis(2-chlorophenyl)methyl)-4-hydroxypiperidin-4-yl)benzyl)-3-methylurea | CHEMBL231866
Type:
Small organic molecule
Emp. Form.:
C27H29Cl2N3O2
Mol. Mass.:
498.444
SMILES:
CNC(=O)NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: