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Target
D(2) dopamine receptor
Ligand
BDBM50280819
Substrate
n/a
Meas. Tech.
ChEBML_61112
IC50
>100±n/a nM
Citation
 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C New indole derivatives as potent and selective serotonin uptake inhibitors Bioorg Med Chem Lett 3:1913-1918 (1993)    Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2
Type:
Enzyme
Mol. Mass.:
50957.64
Organism:
Mouse
Description:
P61168
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50280819
Synonyms:
1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1H,3H-perimidin-2-one | CHEMBL57506
Type:
Small organic molecule
Emp. Form.:
C27H27FN4O
Mol. Mass.:
442.5279
SMILES:
Fc1ccc2[nH]cc(CC3CCN(CCn4c5cccc6cccc([nH]c4=O)c56)CC3)c2c1
Structure:
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