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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50281904
Substrate
n/a
Meas. Tech.
ChEBML_140108
Kd
23±n/a nM
Citation
 Malaska, MJ; Fauq, AH; Kozikowski, AP; Aagaard, PJ; McKinney, M Simplified analogs of himbacine displaying potent binding affinity for muscarinic receptors Bioorg Med Chem Lett 3:1247-1252 (1993)    Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51555.53
Organism:
RAT
Description:
P10980
Residue:
466
Sequence:
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50281904
Synonyms:
2-[(E)-3-(9,10-Dihydro-anthracen-9-yl)-allyl]-1-methyl-piperidine | CHEMBL22071
Type:
Small organic molecule
Emp. Form.:
C23H27N
Mol. Mass.:
317.4672
SMILES:
CN1CCCCC1C\C=C\C1c2ccccc2Cc2ccccc12
Structure:
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