Reaction Details Report a problem with these data
Target
Subtilisin BL
Ligand
BDBM50067885
Substrate
n/a
Meas. Tech.
ChEMBL_197707 (CHEMBL801819)
Ki
802000±n/a nM
Citation
 Stabile, MR; Lai, WG; DeSantis, G; Gold, M; Jones, JB; Mitchinson, C; Bott, RR; Graycar, TP; Liu, CC Probing the specificity of the S1 binding site of M222 mutants of subtilisin B. lentus with boronic acid inhibitors Bioorg Med Chem Lett 6:2501-2506 (1996)    Article 
Target
Name:
Subtilisin BL
Synonyms:
SUBB_LEDLE | Subtilisin
Type:
PROTEIN
Mol. Mass.:
26829.89
Organism:
Bacillus lentus
Description:
ChEMBL_197707
Residue:
269
Sequence:
AQSVPWGISRVQAPAAHNRGLTGSGVKVAVLDTGISTHPDLNIRGGASFVPGEPSTQDGNGHGTHVAGTIAALNNSIGVLGVAPSAELYAVKVLGADGRGAISSIAQGLEWAGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNSGASSISYPARYANAMAVGATDQNNNRASFSQYGAGLDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGAAALVKQKNPSWSNVQIRNHLKNTATSLGSTNLYGSGLVNAEAATR
  
Inhibitor
Name:
BDBM50067885
Synonyms:
4-CARBOXYPHENYLBORONIC ACID | 4-Carboxyphenylboronicacid | 4-boronobenzoic acid | 4-phenylester boronic acid | Boronic acid derivative | CHEMBL82324
Type:
Small organic molecule
Emp. Form.:
C7H7BO4
Mol. Mass.:
165.939
SMILES:
OB(O)c1ccc(cc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: