Reaction Details Report a problem with these data
Target
Fructose-1,6-bisphosphatase 1
Ligand
BDBM50293590
Substrate
n/a
Meas. Tech.
ChEMBL_571203 (CHEMBL1031962)
IC50
571000±n/a nM
Citation
 Heng, S; Gryncel, KR; Kantrowitz, ER A library of novel allosteric inhibitors against fructose 1,6-bisphosphatase. Bioorg Med Chem 17:3916-22 (2009) [PubMed]  Article 
Target
Name:
Fructose-1,6-bisphosphatase 1
Synonyms:
F16P1_PIG | FBP | FBP1 | Fructose-1,6-bisphosphatase | Fructose-1,6-bisphosphatase 1 (FBPase)
Type:
Protein
Mol. Mass.:
36781.07
Organism:
Pig
Description:
Liver FBPase (P00636)
Residue:
338
Sequence:
MTDQAAFDTNIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK
  
Inhibitor
Name:
BDBM50293590
Synonyms:
3-(4-phenylthiazol-2-ylamino)benzoic acid | CHEMBL559631
Type:
Small organic molecule
Emp. Form.:
C16H12N2O2S
Mol. Mass.:
296.344
SMILES:
OC(=O)c1cccc(Nc2nc(cs2)-c2ccccc2)c1
Structure:
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