Reaction Details Report a problem with these data
Target
Fructose-1,6-bisphosphatase 1
Ligand
BDBM50293592
Substrate
n/a
Meas. Tech.
ChEMBL_571203 (CHEMBL1031962)
IC50
1100±n/a nM
Citation
 Heng, S; Gryncel, KR; Kantrowitz, ER A library of novel allosteric inhibitors against fructose 1,6-bisphosphatase. Bioorg Med Chem 17:3916-22 (2009) [PubMed]  Article 
Target
Name:
Fructose-1,6-bisphosphatase 1
Synonyms:
F16P1_PIG | FBP | FBP1 | Fructose-1,6-bisphosphatase | Fructose-1,6-bisphosphatase 1 (FBPase)
Type:
Protein
Mol. Mass.:
36781.07
Organism:
Pig
Description:
Liver FBPase (P00636)
Residue:
338
Sequence:
MTDQAAFDTNIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK
  
Inhibitor
Name:
BDBM50293592
Synonyms:
4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thiazol-4-yl)phenol | CHEMBL483790
Type:
Small organic molecule
Emp. Form.:
C9H8N2OS
Mol. Mass.:
192.238
SMILES:
Nc1nc(cs1)-c1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: