Reaction Details Report a problem with these data
Target
Cytochrome P450 2J2
Ligand
BDBM50305628
Substrate
n/a
Meas. Tech.
ChEMBL_604540 (CHEMBL1074710)
IC50
1400±n/a nM
Citation
 Eldrup, AB; Soleymanzadeh, F; Farrow, NA; Kukulka, A; De Lombaert, S Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase. Bioorg Med Chem Lett 20:571-5 (2010) [PubMed]  Article 
Target
Name:
Cytochrome P450 2J2
Synonyms:
CP2J2_HUMAN | CYP2J2
Type:
Enzyme
Mol. Mass.:
57623.04
Organism:
Human
Description:
P51589
Residue:
502
Sequence:
MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGITISPVSHRLCAVPQV
  
Inhibitor
Name:
BDBM50305628
Synonyms:
CHEMBL589135 | N-(2,4-dichlorobenzyl)-4-phenoxypiperidine-1-carboxamide
Type:
Small organic molecule
Emp. Form.:
C19H20Cl2N2O2
Mol. Mass.:
379.28
SMILES:
Clc1ccc(CNC(=O)N2CCC(CC2)Oc2ccccc2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: