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Target
Adenosine receptor A3
Ligand
BDBM50133368
Substrate
n/a
Meas. Tech.
ChEMBL_685065 (CHEMBL1286681)
Ki
300±n/a nM
Citation
 Giovannoni, MP; Vergelli, C; Cilibrizzi, A; Crocetti, L; Biancalani, C; Graziano, A; Dal Piaz, V; Loza, MI; Cadavid, MI; Díaz, JL; Gavaldà, A Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A(1) adenosine receptor ligands. Bioorg Med Chem 18:7890-9 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
AA3R_BOVIN | ADORA3
Type:
PROTEIN
Mol. Mass.:
35924.51
Organism:
Bos taurus
Description:
ChEMBL_685065
Residue:
317
Sequence:
MPVNSTAVSLASVTYISVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVISLGVTIHFYSCLLMTCLLMIFTHASIMSLLAIAVDRYLRVKLTVRYRRVTTQRRIWLALGLCWLVSFLVGLTPMFGWNMKLSSADKNLTFLPCQFRSVMRMDYMVYFSFFTWILIPLVVMCAIYFDIFYVIRNRLSQNFSGSKETGAFYGREFKTAKSLSLVLFLFALSWLPLSIINCIIYFNGEVPQIVLYLGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVICQPSKSMDPSIEQTSE
  
Inhibitor
Name:
BDBM50133368
Synonyms:
CHEMBL335950 | N-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-2-(naphthalen-1-yl)acetamide | N-[2-Furan-2-yl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-2-naphthalen-1-yl-acetamide
Type:
Small organic molecule
Emp. Form.:
C31H25N7O2
Mol. Mass.:
527.5759
SMILES:
O=C(Cc1cccc2ccccc12)Nc1nc2nn(CCCc3ccccc3)cc2c2nc(nn12)-c1ccco1
Structure:
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