Target
Matrilysin
Ligand
BDBM50332946
Substrate
n/a
Meas. Tech.
ChEMBL_694545 (CHEMBL1635954)
Ki
1500±n/a nM
Citation
 Attolino, ECalderone, VDragoni, EFragai, MRichichi, BLuchinat, CNativi, C Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs). Eur J Med Chem 45:5919-25 (2010) [PubMed]  Article 
Target
Name:
Matrilysin
Synonyms:
MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1
Type:
Enzyme
Mol. Mass.:
29681.54
Organism:
Homo sapiens (Human)
Description:
P09237
Residue:
267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
  
Inhibitor
Name:
BDBM50332946
Synonyms:
CHEMBL1234724 | N-hydroxy-2-(N-(2-hydroxyethyl)-4-methoxyphenylsulfonamido)acetamide | N-hydroxy-N~2~-(2-hydroxyethyl)-N~2~-[(4-methoxyphenyl)sulfonyl]glycinamide
Type:
Small organic molecule
Emp. Form.:
C11H16N2O6S
Mol. Mass.:
304.32
SMILES:
COc1ccc(cc1)S(=O)(=O)N(CCO)CC(=O)NO
Structure:
Search PDB for entries with ligand similarity: