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Target
Phospholipase A2, membrane associated
Ligand
BDBM50055422
Substrate
n/a
Meas. Tech.
ChEMBL_156362 (CHEMBL761692)
IC50
35000±n/a nM
Citation
 Teshirogi, I; Matsutani, S; Shirahase, K; Fujii, Y; Yoshida, T; Tanaka, K; Ohtani, M Synthesis and phospholipase A2 inhibitory activity of thielocin B3 derivatives. J Med Chem 39:5183-91 (1997) [PubMed]  Article 
Target
Name:
Phospholipase A2, membrane associated
Synonyms:
PA2GA_RAT | Phospholipase A2 group IIA | Pla2g2a
Type:
PROTEIN
Mol. Mass.:
16307.95
Organism:
Rat
Description:
ChEMBL_537135
Residue:
146
Sequence:
MKVLLLLAVVIMAFGSIQVQGSLLEFGQMILFKTGKRADVSYGFYGCHCGVGGRGSPKDATDWCCVTHDCCYNRLEKRGCGTKFLTYKFSYRGGQISCSTNQDSCRKQLCQCDKAAAECFARNKKSYSLKYQFYPNKFCKGKTPSC
  
Inhibitor
Name:
BDBM50055422
Synonyms:
3-[[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)-carbonyl]-3-methoxy-2,5,6-trimethylphenoxy]carbonyl]-4-methoxy-5-methylphenyl 5-[[4-[(-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy -2,5,6-trimethylphenoxy]carbonyl]-2,4-dimethoxyphenyl | CHEMBL384003
Type:
Small organic molecule
Emp. Form.:
C62H66O20
Mol. Mass.:
1131.1754
SMILES:
COc1cc(OC)c(cc1Oc1cc(C)c(OC)c(c1)C(=O)Oc1c(C)c(C)c(C(=O)Oc2c(C)c(C)c(C(O)=O)c(OC)c2C)c(OC)c1C)C(=O)Oc1c(C)c(C)c(C(=O)Oc2c(C)c(C)c(C(O)=O)c(OC)c2C)c(OC)c1C
Structure:
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