Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 1 group I member 3
Ligand
BDBM50422492
Substrate
n/a
Meas. Tech.
ChEMBL_48051 (CHEMBL875886)
IC50
39811±n/a nM
Citation
 Jyrkkärinne, J; Mäkinen, J; Gynther, J; Savolainen, H; Poso, A; Honkakoski, P Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor. J Med Chem 46:4687-95 (2003) [PubMed]  Article 
Target
Name:
Nuclear receptor subfamily 1 group I member 3
Synonyms:
Car | Constitutive androstane receptor | NR1I3_MOUSE | Nr1i3 | Nuclear receptor subfamily 1 group I member 3 | Orphan nuclear receptor MB67
Type:
PROTEIN
Mol. Mass.:
40922.30
Organism:
Mus musculus
Description:
ChEMBL_48051
Residue:
358
Sequence:
MTAMLTLETMASEEEYGPRNCVVCGDRATGYHFHALTCEGCKGFFRRTVSKTIGPICPFAGRCEVSKAQRRHCPACRLQKCLNVGMRKDMILSAEALALRRARQAQRRAEKASLQLNQQQKELVQILLGAHTRHVGPMFDQFVQFKPPAYLFMHHRPFQPRGPVLPLLTHFADINTFMVQQIIKFTKDLPLFRSLTMEDQISLLKGAAVEILHISLNTTFCLQTENFFCGPLCYKMEDAVHAGFQYEFLESILHFHKNLKGLHLQEPEYVLMAATALFSPDRPGVTQREEIDQLQEEMALILNNHIMEQQSRLQSRFLYAKLMGLLADLRSINNAYSYELQRLEELSAMTPLLGEICS
  
Inhibitor
Name:
BDBM50422492
Synonyms:
CHEMBL143192
Type:
Small organic molecule
Emp. Form.:
C20H28O3
Mol. Mass.:
316.4345
SMILES:
CC12CCC3C(CCC4=CC(=O)CCC34C)C1CC[C@@H]2C(O)=O |t:8|
Structure:
Search PDB for entries with ligand similarity: