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Target
Nociceptin receptor
Ligand
BDBM50068133
Substrate
n/a
Meas. Tech.
ChEMBL_378705 (CHEMBL853453)
Ki
1028±n/a nM
Citation
 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners. Bioorg Med Chem Lett 16:4291-5 (2006) [PubMed]  Article 
Target
Name:
Nociceptin receptor
Synonyms:
OOR | OPRL1 | OPRX_CAVPO
Type:
PROTEIN
Mol. Mass.:
40796.89
Organism:
Cavia porcellus
Description:
ChEMBL_444577
Residue:
370
Sequence:
MESLFPAPFWEVLYGSHLQGNLSLLSPNHSGLPPHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQATDILLGFWPFGNTLCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALALVVGVPVAIMGSAQVEDEEIECLVEIPDPQDYWGPVFAVSIFLFSFIIPVLIISVCYSLMIRRLHGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETTVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALHREMQVSDRVRSIAKDVALGCKTTETVPRPA
  
Inhibitor
Name:
BDBM50068133
Synonyms:
(4S,7S,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-chloro-benzyl)-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid | CHEMBL143939
Type:
Small organic molecule
Emp. Form.:
C30H38ClN5O7S2
Mol. Mass.:
680.235
SMILES:
CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccc(Cl)cc2)C(=O)N[C@H]1C(O)=O
Structure:
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