Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50212653
Substrate
n/a
Meas. Tech.
ChEMBL_436711 (CHEMBL905020)
EC50
929±n/a nM
Citation
 Tan, ES; Miyakawa, M; Bunzow, JR; Grandy, DK; Scanlan, TS Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1. J Med Chem 50:2787-98 (2007) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50212653
Synonyms:
2-(4-phenoxyphenyl)but-3-yn-1-amine hydrochloride | CHEMBL541905
Type:
Small organic molecule
Emp. Form.:
C16H15NO
Mol. Mass.:
237.2964
SMILES:
NCC(C#C)c1ccc(Oc2ccccc2)cc1 |w:2.1|
Structure:
Search PDB for entries with ligand similarity: