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Target
MO15-related protein kinase Pfmrk
Ligand
BDBM15210
Substrate
n/a
Meas. Tech.
ChEMBL_456708 (CHEMBL923066)
IC50
70000±n/a nM
Citation
 Woodard, CL; Keenan, SM; Gerena, L; Welsh, WJ; Geyer, JA; Waters, NC Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk. Bioorg Med Chem Lett 17:4961-6 (2007) [PubMed]  Article 
Target
Name:
MO15-related protein kinase Pfmrk
Synonyms:
Protein kinase Pfmrk
Type:
PROTEIN
Mol. Mass.:
37992.30
Organism:
malaria parasite P. falciparum
Description:
ChEMBL_640752
Residue:
324
Sequence:
MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLLREIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQILNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLNLTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFLLGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAEDAMKHRYFFNDPLPCDISQLPFNDL
  
Inhibitor
Name:
BDBM15210
Synonyms:
CHEMBL148333 | H-8 | Lopac-M-9656 | N-(2-methylaminoethyl)isoquinoline-5-sulfonamide | N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C12H15N3O2S
Mol. Mass.:
265.331
SMILES:
CNCCNS(=O)(=O)c1cccc2cnccc12
Structure:
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