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Target
Melanocortin receptor 3
Ligand
BDBM50374116
Substrate
n/a
Meas. Tech.
ChEMBL_468952 (CHEMBL951291)
EC50
320±n/a nM
Citation
 Joseph, CG; Wilson, KR; Wood, MS; Sorenson, NB; Phan, DV; Xiang, Z; Witek, RM; Haskell-Luevano, C The 1,4-benzodiazepine-2,5-dione small molecule template results in melanocortin receptor agonists with nanomolar potencies. J Med Chem 51:1423-31 (2008) [PubMed]  Article 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R_MOUSE | Mc3r
Type:
PROTEIN
Mol. Mass.:
35808.24
Organism:
Mus musculus
Description:
ChEMBL_1498848
Residue:
323
Sequence:
MNSSCCLSSVSPMLPNLSEHPAAPPASNRSGSGFCEQVFIKPEVFLALGIVSLMENILVILAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIAVINSDSLTLEDQFIQHMDNIFDSMICISLVASICNLLAIAIDRYVTIFYALRYHSIMTVRKALTLIGVIWVCCGICGVMFIIYSESKMVIVCLITMFFAMVLLMGTLYIHMFLFARLHVQRIAVLPPAGVVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFKEILCGCNSMNLG
  
Inhibitor
Name:
BDBM50374116
Synonyms:
CHEMBL270270
Type:
Small organic molecule
Emp. Form.:
C20H22ClN3O2
Mol. Mass.:
371.861
SMILES:
NCCCCC1NC(=O)c2ccc(Cl)cc2N(Cc2ccccc2)C1=O |w:5.4|
Structure:
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