Reaction Details Report a problem with these data
Target
Somatostatin receptor type 2
Ligand
BDBM50294224
Substrate
n/a
Meas. Tech.
ChEMBL_575181 (CHEMBL1024528)
IC50
>1000±n/a nM
Citation
 Erchegyi, J; Cescato, R; Grace, CR; Waser, B; Piccand, V; Hoyer, D; Riek, R; Rivier, JE; Reubi, JC Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues. J Med Chem 52:2733-46 (2009) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50294224
Synonyms:
(4R,7S,10S,13S,16S,19R)-19-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-7,16-dibenzyl-10-(4-((isopropylamino)methyl)benzyl)-13-(N-methyl-2-naphthamido)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide | CHEMBL558935
Type:
Small organic molecule
Emp. Form.:
C64H75N11O11S2
Mol. Mass.:
1238.477
SMILES:
CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H](N)Cc2ccc(O)cc2)N(C)C(=O)c2ccc3ccccc3c2)cc1 |r|
Structure:
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