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Target
Somatostatin receptor type 1
Ligand
BDBM50294248
Substrate
n/a
Meas. Tech.
ChEMBL_575180 (CHEMBL1024527)
IC50
356±n/a nM
Citation
 Erchegyi, J; Cescato, R; Grace, CR; Waser, B; Piccand, V; Hoyer, D; Riek, R; Rivier, JE; Reubi, JC Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues. J Med Chem 52:2733-46 (2009) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM50294248
Synonyms:
(2S)-2-{[(4R,7S,10S,13R,16S,19S)-19-amino-16-benzyl-7-[(4-hydroxy-3-iodophenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-10-({4-[(propan-2-ylamino)methyl]phenyl}methyl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]formamido}-3-(naphthalen-2-yl)propanamide | CHEMBL563124
Type:
Small organic molecule
Emp. Form.:
C61H67IN10O8S2
Mol. Mass.:
1259.281
SMILES:
CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](N)CSSC[C@H](NC(=O)[C@H](Cc3ccc(O)c(I)c3)NC2=O)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(N)=O)cc1 |r|
Structure:
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