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Target
Kappa-type opioid receptor
Ligand
BDBM50341303
Substrate
n/a
Meas. Tech.
ChEMBL_742583 (CHEMBL1769426)
Ki
0.710000±n/a nM
Citation
 Zhang, T; Yan, Z; Sromek, A; Knapp, BI; Scrimale, T; Bidlack, JM; Neumeyer, JL Aminothiazolomorphinans with mixed¿ andµ opioid activity. J Med Chem 54:1903-13 (2011) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Human
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50341303
Synonyms:
CHEMBL1766041 | N'-Methyl-aminothiazolo[5,4-b]-N-fluoropropylmorphinan
Type:
Small organic molecule
Emp. Form.:
C21H28FN3S
Mol. Mass.:
373.531
SMILES:
CNc1nc2cc3c(C[C@@H]4[C@@H]5CCCC[C@]35CCN4CCCF)cc2s1 |r|
Structure:
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