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Target
Cytochrome P450 1A1
Ligand
BDBM50017716
Substrate
n/a
Meas. Tech.
ChEMBL_36220 (CHEMBL647916)
IC50
22000±n/a nM
Citation
 Little, PJ; Ryan, AJ Inhibitors of hepatic mixed-function oxidases. 4. Effects of benzimidazole and related compounds on aryl hydrocarbon hydroxylase activity from phenobarbitone and 3-methylcholanthrene induced rats. J Med Chem 25:622-6 (1982) [PubMed]  Article 
Target
Name:
Cytochrome P450 1A1
Synonyms:
CP1A1_RAT | Cyp1a-1 | Cyp1a1
Type:
PROTEIN
Mol. Mass.:
59401.56
Organism:
Rattus norvegicus
Description:
ChEMBL_774160
Residue:
524
Sequence:
MPSVYGFPAFTSATELLLAVTTFCLGFWVVRVTRTWVPKGLKSPPGPWGLPFIGHVLTLGKNPHLSLTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLIANGQSMTFNPDSGPLWAARRRLAQNALKSFSIASDPTLASSCYLEEHVSKEAEYLISKFQKLMAEVGHFDPFKYLVVSVANVICAICFGRRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPILRYLPNSSLDAFKDLNKKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRRLDENANVQLSDDKVITIVFDLFGAGFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNHDQELWGDPNEFRPERFLTSSGTLDKHLSEKVILFGLGKRKCIGETIGRLEVFLFLAILLQQMEFNVSPGEKVDMTPAYGLTLKHARCEHFQVQMRSSGPQHLQA
  
Inhibitor
Name:
BDBM50017716
Synonyms:
2,2-Diphenyl-pentanoic acid 2-diethylamino-ethyl ester | 2-(diethylamino)ethyl 2,2-diphenylpentanoate | 2-Benzhydryl-pentanoic acid 2-diethylamino-ethyl ester | CHEMBL282567 | PROADIFEN HYDROCHLORIDE
Type:
Small organic molecule
Emp. Form.:
C23H31NO2
Mol. Mass.:
353.4977
SMILES:
CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: