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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50118340
Substrate
n/a
Meas. Tech.
ChEMBL_628657 (CHEMBL1106423)
Ki
37.15±n/a nM
Citation
 Weber, KC; Salum, LB; Honório, KM; Andricopulo, AD; da Silva, AB Pharmacophore-based 3D QSAR studies on a series of high affinity 5-HT1A receptor ligands. Eur J Med Chem 45:1508-14 (2010) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50118340
Synonyms:
1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-5-yl)piperazin-1-yl)propan-1-ol | 1-Benzo[b]thiophen-3-yl-3-(4-quinolin-5-yl-piperazin-1-yl)-propan-1-ol | CHEMBL133335
Type:
Small organic molecule
Emp. Form.:
C24H25N3OS
Mol. Mass.:
403.54
SMILES:
OC(CCN1CCN(CC1)c1cccc2ncccc12)c1csc2ccccc12
Structure:
Search PDB for entries with ligand similarity: