Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 1
Ligand
BDBM50420177
Substrate
n/a
Meas. Tech.
ChEMBL_835933 (CHEMBL2077071)
IC50
7337000±n/a nM
Citation
 Kakehi, M; Koyabu, N; Nakamura, T; Uchiumi, T; Kuwano, M; Ohtani, H; Sawada, Y Functional characterization of mouse cation transporter mOCT2 compared with mOCT1. Biochem Biophys Res Commun 296:644-50 (2002) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 1
Synonyms:
Lx1 | Oct1 | Organic cation transporter 1 | S22A1_MOUSE | Slc22a1 | mOCT1
Type:
PROTEIN
Mol. Mass.:
61521.43
Organism:
Mouse
Description:
ChEMBL_1279071
Residue:
556
Sequence:
MPTVDDVLEHVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPDHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEASFLSQCMKYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSLSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKNRKVPPADLKMMCLEEDASERRSPSFADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVAGAACLLMIFIPHELHWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALPLILFGVLGLSAGAVTLLLPETKGVALPETIEEAENLGRRKSKAKENTIYLQVQTGKSPHT
  
Inhibitor
Name:
BDBM50420177
Synonyms:
NICOTINYL METHYLAMIDE
Type:
Small organic molecule
Emp. Form.:
C7H8N2O
Mol. Mass.:
136.1512
SMILES:
CNC(=O)c1cccnc1
Structure:
Search PDB for entries with ligand similarity: