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Target
Somatostatin receptor type 2
Ligand
BDBM50423339
Substrate
n/a
Meas. Tech.
ChEMBL_456105 (CHEMBL888114)
Kd
7079±n/a nM
Citation
 Hurth, K; Enz, A; Floersheim, P; Gentsch, C; Hoyer, D; Langenegger, D; Neumann, P; Pfäffli, P; Sorg, D; Swoboda, R; Vassout, A; Troxler, T SAR of the arylpiperazine moiety of obeline somatostatin sst1 receptor antagonists. Bioorg Med Chem Lett 17:3988-91 (2007) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS2R | SSR2_RAT | Somatostatin receptor | Somatostatin receptor 2 | Somatostatin receptor type 2 | Sstr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41212.21
Organism:
Rat
Description:
SOMATOSTATIN SST2 SSTR2 RAT::P30680
Residue:
369
Sequence:
MELTSEQFNGSQVWIPSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGAEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50423339
Synonyms:
CHEMBL250920
Type:
Small organic molecule
Emp. Form.:
C27H32N6O2
Mol. Mass.:
472.582
SMILES:
COc1cccc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3cc4nccnc4cn3)Cc12
Structure:
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