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Target
Monoglyceride lipase
Ligand
BDBM50063528
Substrate
n/a
Meas. Tech.
ChEMBL_1463376 (CHEMBL3399685)
IC50
100000±n/a nM
Citation
 Finnegan, DF; Shelnut, EL; Nikas, SP; Chiang, N; Serhan, CN; Makriyannis, A Novel tail and head group prostamide probes. Bioorg Med Chem Lett 25:1228-31 (2015) [PubMed]  Article 
Target
Name:
Monoglyceride lipase
Synonyms:
HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN
Type:
Hydrolase
Mol. Mass.:
33264.56
Organism:
Homo sapiens (Human)
Description:
Human recombinant MGL (Cayman Chemical, cat# 10008354).
Residue:
303
Sequence:
MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTASPP
  
Inhibitor
Name:
BDBM50063528
Synonyms:
CHEMBL3398545
Type:
Small organic molecule
Emp. Form.:
C25H35NO5
Mol. Mass.:
429.5491
SMILES:
OCCNC(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\[C@@H](O)CCc2ccccc2)[C@H](O)CC1=O |r|
Structure:
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