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Target
Histamine H2 receptor
Ligand
BDBM50220142
Substrate
n/a
Meas. Tech.
ChEMBL_85661 (CHEMBL702652)
Ki
56234±n/a nM
Citation
 Faghih, R; Dwight, W; Gentles, R; Phelan, K; Esbenshade, TA; Ireland, L; Miller, TR; Kang, CH; Fox, GB; Gopalakrishnan, SM; Hancock, AA; Bennani, YL Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 1. Bioorg Med Chem Lett 12:2031-4 (2002) [PubMed]  Article 
Target
Name:
Histamine H2 receptor
Synonyms:
Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40115.31
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
359
Sequence:
MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
  
Inhibitor
Name:
BDBM50220142
Synonyms:
CHEMBL62066
Type:
Small organic molecule
Emp. Form.:
C19H28N2O4
Mol. Mass.:
348.4366
SMILES:
CCOC(=O)N1CCN(CCCOc2ccc(cc2)C(=O)CC)CC1
Structure:
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