Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM85775
Substrate
n/a
Ki
3425.4±n/a nM
Comments
PDSP_2053
Citation
 Durand, IH; Green, RD Cloning of a chick A3 adenosine receptor: characterization of ligand binding and receptor-effector coupling of chick A1 and A3 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 363:81-6 (2001) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_CHICK | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36337.19
Organism:
Chick
Description:
ADENOSINE A1 ADORA1 Chick::P49892
Residue:
324
Sequence:
MAQSVTAFQAAYISIEVLIALVSVPGNILVIWAVKMNQALRDATFCFIVSLAVADVAVGALVIPLAIIINIGPQTEFYSCLMMACPVLILTESSILALLAIAVDRYLRVKIPVRYKSVVTPRRAAVAIACCWIVSFLVGLTPMFGWNNLNKVLGTRDLNVSHSEFVIKCQFETVISMEYMVYFNFFVWVLPPLLLMLLIYLEVFNLIRTQLNKKVSSSSNDPQKYYGKELKIAKSLALVLFLFALSWLPLHILNCITLFCPSCKTPHILTYIAIFLTHGNSAMNPIVYAFRIKKFRTAFLQIWNQYFCCKTNKSSSSSTAETVN
  
Inhibitor
Name:
BDBM85775
Synonyms:
CHEMBL315984 | MRS1097
Type:
Small organic molecule
Emp. Form.:
C26H27NO4
Mol. Mass.:
417.4969
SMILES:
CCOC(=O)C1C(\C=C\c2ccccc2)C(C(=O)OCC)=C(N=C1C)c1ccccc1 |c:21,23|
Structure:
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