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Target
Neuronal acetylcholine receptor subunit alpha-6
Ligand
BDBM86243
Substrate
n/a
Ki
4520±n/a nM
Comments
PDSP_3078
Citation
 Vailati, S; Moretti, M; Longhi, R; Rovati, GE; Clementi, F; Gotti, C Developmental expression of heteromeric nicotinic receptor subtypes in chick retina. Mol Pharmacol 63:1329-37 (2003) [PubMed]  Article 
Target
Name:
Neuronal acetylcholine receptor subunit alpha-6
Synonyms:
ACHA6_CHICK | CHRNA6 | Cholinergic, Nicotinic Alpha6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57501.33
Organism:
Chick
Description:
Cholinergic, Nicotinic Alpha6 0 Chick::P49581
Residue:
494
Sequence:
MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVTVHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRRDPREYDGIEFVRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLEQEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLKWMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEVEDDWKYVAMVIDRVFLWVFIILCVFGTAGLFIQPLIADT
  
Inhibitor
Name:
BDBM86243
Synonyms:
CAS_17360 | MG624 | NSC_17360
Type:
Small organic molecule
Emp. Form.:
C22H30NO
Mol. Mass.:
324.4792
SMILES:
CC[N+](CC)(CC)CCOc1ccc(C=Cc2ccccc2)cc1 |w:14.13|
Structure:
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