Reaction Details Report a problem with these data
Target
Chymotrypsin-C
Ligand
BDBM87059
Substrate
n/a
Meas. Tech.
Enzyme Inhibition Assay
pH
7.6±0
Temperature
298.15±0 K
Ki
8.24e+3± 1.1e+2 nM
Citation
 Arif Lodhi, M; Iqbal Choudhary, M; Malik, A; Ahmad, S alpha-Chymotrypsin inhibition studies on the lignans from Vitex negundo Linn. J Enzyme Inhib Med Chem 23:400-5 (2008) [PubMed]  Article 
Target
Name:
Chymotrypsin-C
Synonyms:
CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C
Type:
Enzyme
Mol. Mass.:
29487.98
Organism:
Human
Description:
Q99895
Residue:
268
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
  
Inhibitor
Name:
BDBM87059
Synonyms:
CHEMBL247767 | Chymostatin
Type:
Small organic molecule
Emp. Form.:
C31H41N7O6
Mol. Mass.:
607.7005
SMILES:
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)N[C@@H](Cc1ccccc1)C(O)=O)C1CCNC(N)=N1)C(=O)N[C@@H](Cc1ccccc1)C=O |c:30|
Structure:
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