Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89102
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
74640±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89102
Synonyms:
1-mesyl-N-(6-methyl-1,3-benzothiazol-2-yl)pyrrolidine-2-carboxamide | MLS-0463370.0001 | N-(6-methyl-1,3-benzothiazol-2-yl)-1-methylsulfonyl-2-pyrrolidinecarboxamide | N-(6-methyl-1,3-benzothiazol-2-yl)-1-methylsulfonyl-pyrrolidine-2-carboxamide | N-(6-methyl-1,3-benzothiazol-2-yl)-1-methylsulfonylpyrrolidine-2-carboxamide | cid_18093477
Type:
Small organic molecule
Emp. Form.:
C14H17N3O3S2
Mol. Mass.:
339.433
SMILES:
Cc1ccc2nc(NC(=O)C3CCCN3S(C)(=O)=O)sc2c1
Structure:
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