Reaction Details Report a problem with these data
Target
Prostaglandin G/H synthase 1 [582-599]
Ligand
BDBM93104
Substrate
n/a
Meas. Tech.
In Vitro COX Inhibition Assay
IC50
>1.00e+5±n/a nM
Citation
 Zarghi, A; Arefi, H; Dadrass, OG; Torabi, S Design and synthesis of new 2-aryl, 3-benzyl- (1,3-oxazolidine or 1,3-thiazolidine)-4-ones as selective cyclooxygenase (COX-2) inhibitor Med Chem Res 19:782-793 (2009)   
Target
Name:
Prostaglandin G/H synthase 1 [582-599]
Synonyms:
COX-1 | COX1 | Cyclooxygenase | Cyclooxygenase-1 | Cyclooxygenase-1 (COX-1) | PGH synthase 1 | PGH1_HUMAN | PGHS-1 | PHS 1 | PTGS1 | Prostaglandin G/H synthase 1 | Prostaglandin H2 synthase 1 | Prostaglandin-endoperoxide synthase 1
Type:
Protein
Mol. Mass.:
1879.89
Organism:
Homo sapiens (Human)
Description:
Q6LCE7
Residue:
18
Sequence:
PDASQDDGPAVERPSTEL
  
Inhibitor
Name:
BDBM93104
Synonyms:
COX inhibitor, 5b
Type:
Small molecule
Emp. Form.:
C16H15NOS
Mol. Mass.:
269.361
SMILES:
O=C1CSC(N1Cc1ccccc1)c1ccccc1
Structure:
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