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Target
Protein skinhead-1
Ligand
BDBM93804
Substrate
n/a
IC50
24400±n/a nM
Citation
 PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
  
Inhibitor
Name:
BDBM93804
Synonyms:
2-(2-(4-fluorophenyl)-2H-tetrazol-5-yl)thiazole | 2-[2-(4-fluorophenyl)-1,2,3,4-tetrazol-5-yl]-1,3-thiazole | 2-[2-(4-fluorophenyl)-5-tetrazolyl]thiazole | 2-[2-(4-fluorophenyl)tetrazol-5-yl]-1,3-thiazole | 2-[2-(4-fluorophenyl)tetrazol-5-yl]thiazole | MLS000697784 | SMR000327361 | cid_16066570
Type:
Small organic molecule
Emp. Form.:
C10H6FN5S
Mol. Mass.:
247.252
SMILES:
Fc1ccc(cc1)-n1nnc(n1)-c1nccs1
Structure:
Search PDB for entries with ligand similarity: