Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93804
Substrate
n/a
IC50
49970±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93804
Synonyms:
2-(2-(4-fluorophenyl)-2H-tetrazol-5-yl)thiazole | 2-[2-(4-fluorophenyl)-1,2,3,4-tetrazol-5-yl]-1,3-thiazole | 2-[2-(4-fluorophenyl)-5-tetrazolyl]thiazole | 2-[2-(4-fluorophenyl)tetrazol-5-yl]-1,3-thiazole | 2-[2-(4-fluorophenyl)tetrazol-5-yl]thiazole | MLS000697784 | SMR000327361 | cid_16066570
Type:
Small organic molecule
Emp. Form.:
C10H6FN5S
Mol. Mass.:
247.252
SMILES:
Fc1ccc(cc1)-n1nnc(n1)-c1nccs1
Structure:
Search PDB for entries with ligand similarity: