Reaction Details
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Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM78178
Substrate
n/a
IC50
29000±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM78178
Synonyms:
3-[2-(3-Hydroxy-phenylamino)-thiazol-4-yl]-6-methoxy-chromen-2-one | 3-[2-(3-hydroxyanilino)-1,3-thiazol-4-yl]-6-methoxychromen-2-one | 3-[2-(3-hydroxyanilino)-4-thiazolyl]-6-methoxy-1-benzopyran-2-one | 3-[2-(3-hydroxyanilino)thiazol-4-yl]-6-methoxy-coumarin | 3-[2-[(3-hydroxyphenyl)amino]-1,3-thiazol-4-yl]-6-methoxy-chromen-2-one | MLS000548677 | SMR000172285 | cid_1077600
Type:
Small organic molecule
Emp. Form.:
C19H14N2O4S
Mol. Mass.:
366.39
SMILES:
COc1ccc2oc(=O)c(cc2c1)-c1csc(Nc2cccc(O)c2)n1
Structure:
