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Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95355
Substrate
n/a
IC50
113542±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bovine
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95355
Synonyms:
4-((E)-{[(4-{[(2E)-2-(4-carboxybenzylidene)hydrazino]carbonyl}-3,5-dimethyl-1H-pyrrol-2-yl)carbonyl]hydrazono}methyl)benzoic acid | 4-[(E)-[[5-[[(E)-(4-carboxybenzylidene)amino]carbamoyl]-2,4-dimethyl-1H-pyrrole-3-carbonyl]hydrazono]methyl]benzoic acid | 4-[(E)-[[5-[[(E)-(4-carboxyphenyl)methylideneamino]carbamoyl]-2,4-dimethyl-1H-pyrrol-3-yl]carbonylhydrazinylidene]methyl]benzoic acid | 4-[(E)-[[5-[[(E)-(4-carboxyphenyl)methylideneamino]carbamoyl]-2,4-dimethyl-1H-pyrrole-3-carbonyl]hydrazinylidene]methyl]benzoic acid | 4-[(E)-[[[5-[[(2E)-2-[(4-carboxyphenyl)methylidene]hydrazinyl]-oxomethyl]-2,4-dimethyl-1H-pyrrol-3-yl]-oxomethyl]hydrazinylidene]methyl]benzoic acid | MLS000585851 | SMR000207632 | cid_20846810
Type:
Small organic molecule
Emp. Form.:
C24H21N5O6
Mol. Mass.:
475.4534
SMILES:
Cc1[nH]c(C(=O)N\N=C\c2ccc(cc2)C(O)=O)c(C)c1C(=O)N\N=C\c1ccc(cc1)C(O)=O
Structure:
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