Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95386
Substrate
n/a
IC50
91238±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bovine
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95386
Synonyms:
4-[(9,10-diketo-2-anthryl)sulfonylamino]benzoic acid | 4-[(9,10-dioxo-2-anthracenyl)sulfonylamino]benzoic acid | 4-[(9,10-dioxoanthracen-2-yl)sulfonylamino]benzoic acid | 4-[[9,10-bis(oxidanylidene)anthracen-2-yl]sulfonylamino]benzoic acid | 4-{[(9,10-dioxo-9,10-dihydro-2-anthracenyl)sulfonyl]amino}benzoic acid | MLS000704597 | SMR000231989 | cid_7113151
Type:
Small organic molecule
Emp. Form.:
C21H13NO6S
Mol. Mass.:
407.396
SMILES:
OC(=O)c1ccc(NS(=O)(=O)c2ccc3C(=O)c4ccccc4C(=O)c3c2)cc1
Structure:
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