Reaction Details
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Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95389
Substrate
n/a
IC50
67697±n/a nM
Citation
PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bovine
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
Inhibitor
Name:
BDBM95389
Synonyms:
2-(7-Morpholin-4-yl-4-nitro-benzo[1,2,5]oxadiazol-5-ylamino)-phenol | 6-[(7-morpholin-4-yl-4-nitro-1,3-dihydro-2,1,3-benzoxadiazol-5-yl)imino]cyclohexa-2,4-dien-1-one | 6-[(7-morpholino-4-nitro-1,3-dihydrobenzofurazan-5-yl)imino]cyclohexa-2,4-dien-1-one | 6-[[7-(4-morpholinyl)-4-nitro-1,3-dihydro-2,1,3-benzoxadiazol-5-yl]imino]-1-cyclohexa-2,4-dienone | MLS000332132 | SMR000221550 | cid_6054788
Type:
Small organic molecule
Emp. Form.:
C16H15N5O5
Mol. Mass.:
357.3208
SMILES:
[O-]c1ccccc1Nc1cc(N2CCOCC2)c2[nH+]onc2c1[N+]([O-])=O
Structure:
