Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96706
Substrate
n/a
EC50
>29879±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96706
Synonyms:
5-[2,5-dimethyl-1-(2-oxolanylmethyl)-3-pyrrolyl]-N-(2-phenylethyl)-6H-1,3,4-thiadiazin-2-amine | 5-[2,5-dimethyl-1-(oxolan-2-ylmethyl)pyrrol-3-yl]-N-(2-phenylethyl)-6H-1,3,4-thiadiazin-2-amine | MLS000516835 | SMR000342950 | [5-[2,5-dimethyl-1-(tetrahydrofurfuryl)pyrrol-3-yl]-6H-1,3,4-thiadiazin-2-yl]-phenethyl-amine | cid_4591140
Type:
Small organic molecule
Emp. Form.:
C22H28N4OS
Mol. Mass.:
396.549
SMILES:
Cc1cc(c(C)n1CC1CCCO1)C1=NN=C(NCCc2ccccc2)SC1 |t:15,17|
Structure:
Search PDB for entries with ligand similarity: