Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM47589
Substrate
n/a
IC50
>29910±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM47589
Synonyms:
1-Ethyl-6-fluoro-4-oxo-7-{N'-[1-phenyl-meth-(E)-ylidene]-hydrazino}-1,4-dihydro-quinoline-3-carboxylic acid | 1-ethyl-6-fluoranyl-4-oxidanylidene-7-[2-(phenylmethylidene)hydrazinyl]quinoline-3-carboxylic acid | 1-ethyl-6-fluoro-4-oxo-7-[2-(phenylmethylene)hydrazinyl]-3-quinolinecarboxylic acid | 7-(2-benzylidenehydrazinyl)-1-ethyl-6-fluoro-4-oxoquinoline-3-carboxylic acid | 7-(N'-benzalhydrazino)-1-ethyl-6-fluoro-4-keto-quinoline-3-carboxylic acid | 7-[(N''E)-N''-benzalhydrazino]-1-ethyl-6-fluoro-4-keto-quinoline-3-carboxylic acid | 7-[(N'E)-N'-benzalhydrazino]-1-ethyl-6-fluoro-4-keto-quinoline-3-carboxylic acid | MLS000589332 | SMR000212831 | cid_3726683
Type:
Small organic molecule
Emp. Form.:
C19H16FN3O3
Mol. Mass.:
353.347
SMILES:
CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N=NCc1ccccc1 |w:17.18|
Structure:
Search PDB for entries with ligand similarity: