Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM103448
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
0.091±0.0 nM
Citation
 Uchikawa, O; Koike, T; Hoashi, Y; Takai, T Tricyclic compound and pharmaceutical use thereof US Patent  US8552037 Publication Date 10/8/2013 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Human
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM103448
Synonyms:
US8552037, 95
Type:
Small organic molecule
Emp. Form.:
C24H28N2O2
Mol. Mass.:
376.4913
SMILES:
CC(=O)NCCC1CCc2ccc3nc(CCCCc4ccccc4)oc3c12
Structure:
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