Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM200211
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
823±172 nM
Citation
 Rodríguez, D; Chakraborty, S; Warnick, E; Crane, S; Gao, ZG; O'Connor, R; Jacobson, KA; Carlsson, J Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists ACS Chem Biol 11:2763-2772 (2016) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM200211
Synonyms:
Adenosine receptor agonist, 7
Type:
Small organic molecule
Emp. Form.:
C12H15N3O4
Mol. Mass.:
265.2652
SMILES:
Nc1cccc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: