Reaction Details Report a problem with these data
Target
D-amino-acid oxidase
Ligand
BDBM258352
Substrate
n/a
Meas. Tech.
In Vitro Assay
pH
8.5±n/a
Temperature
298.15±n/a K
IC50
600±n/a nM
Comments
extracted
Citation
 Tsukamoto, T; Slusher, BS; Ferraris, DV; Rojas, C; Hin, N; Duvall, B Inhibitors of D-amino acid oxidase US Patent  US9505753 Publication Date 11/29/2016 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-Amino Acid Oxidase (DAAO) | D-amino-acid oxidase (DAAO) | DAMOX | DAO | OXDA_PIG
Type:
Flavoprotein
Mol. Mass.:
39338.01
Organism:
Sus scrofa (pig)
Description:
Homodimer.
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGGTFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL
  
Inhibitor
Name:
BDBM258352
Synonyms:
US9505753, 10u
Type:
Small organic molecule
Emp. Form.:
C15H13N3O3
Mol. Mass.:
283.282
SMILES:
Cc1ccc2ccccc2c1Cn1nc(O)c(=O)[nH]c1=O
Structure:
Search PDB for entries with ligand similarity: