Reaction Details Report a problem with these data
Target
Interleukin-2
Ligand
BDBM412498
Substrate
n/a
Meas. Tech.
Human ELISA assay
IC50
21.0±n/a nM
Citation
 Chen, S; Bohnert, G; Jiang, J; Xia, Z Compounds for inflammation and immune-related uses US Patent  US10399967 Publication Date 9/3/2019 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Human
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM412498
Synonyms:
N-(5-(2-chloro-5-(1-methyl-1H- pyrazol-4-yl)phenyl)pyrazin-2-yl)-5- ethyl-4-methylnicotinamide | US10399967, Compound 131
Type:
Small organic molecule
Emp. Form.:
C23H21ClN6O
Mol. Mass.:
432.905
SMILES:
CCc1cncc(C(=O)Nc2cnc(cn2)-c2cc(ccc2Cl)-c2cnn(C)c2)c1C
Structure:
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