Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM250393
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
0.500±n/a nM
Citation
 Groebke Zbinden, K; Norcross, R; Pflieger, P Substituted benzamides US Patent  US10501411 Publication Date 12/10/2019 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM250393
Synonyms:
US10501411, Example 303 | US11697636, Example 303 | US9452980, 303
Type:
Small organic molecule
Emp. Form.:
C17H18ClN3O2
Mol. Mass.:
331.797
SMILES:
Clc1cccc(NC(=O)Nc2ccc(cc2)C2CNCCO2)c1
Structure:
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