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Target
Mu-type opioid receptor
Ligand
BDBM518593
Substrate
n/a
Meas. Tech.
Detection of MOR cAMP Agonist Activity
EC50
0.040±n/a nM
Citation
 Zhang, Y; Wu, W; Yang, G; Li, Z; Sun, J; Li, J; Li, J; Chen, S 2,6-dioxaspiro [4,5] decane derivatives and preparation method therefor and pharmaceutical applications thereof US Patent  US11124523 Publication Date 9/21/2021 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM518593
Synonyms:
US11124523, Example (+)-28b
Type:
Small organic molecule
Emp. Form.:
C24H29FN2O2
Mol. Mass.:
396.4977
SMILES:
Fc1ccc(nc1)[C@]1(CCN[C@H]2CCc3ccccc23)CCO[C@]2(CCOC2)C1 |r|
Structure:
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