Reaction Details Report a problem with these data
Target
Bromodomain-containing protein 3 [326-398]
Ligand
BDBM50527819
Substrate
n/a
Meas. Tech.
Plate-Based Time-Resolved Fluorescence Energy Transfer (TR-FRET) Assays
IC50
2495±n/a nM
Citation
 Zhou, J; Brasier, AR; Tian, B; Liu, Z; Chen, H; Rytting, E Inhibitors of bromodomain-containing protein 4 (BRD4) US Patent  US11117865 Publication Date 9/14/2021 
Target
Name:
Bromodomain-containing protein 3 [326-398]
Synonyms:
BRD3 | BRD3_HUMAN | Bromodomain-containing protein 3 (BRD3)(BD2) | Bromodomain-containing protein 3 Bromo 2 domain(BRD3 BD2) | KIAA0043 | RING3L
Type:
n/a
Mol. Mass.:
8553.07
Organism:
Homo sapiens (Human)
Description:
BD2 (326-398 aa) of Q15059
Residue:
73
Sequence:
KHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVV
  
Inhibitor
Name:
BDBM50527819
Synonyms:
CHEMBL4557050 | US11117865, Compound ZL0516
Type:
Small organic molecule
Emp. Form.:
C27H34N2O6
Mol. Mass.:
482.5687
SMILES:
COc1cc(OC)c2c(c1)oc(cc2=O)-c1cc(C)c(OC[C@H](O)CN2CCN(C)CC2)c(C)c1 |r|
Structure:
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