Reaction Details Report a problem with these data
Target
Chloride intracellular channel protein 1
Ligand
BDBM525314
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
9000±n/a nM
Citation
 Koster, AK; Du Bois, J; Maduke, MC Compositions and methods to modulate chloride ion channel activity US Patent  US11173137 Publication Date 11/16/2021 
Target
Name:
Chloride intracellular channel protein 1
Synonyms:
CLIC1 | CLIC1_HUMAN | Chloride channel ABP | G6 | NCC27 | Nuclear chloride ion channel 27 | Regulatory nuclear chloride ion channel protein | hRNCC
Type:
Protein
Mol. Mass.:
26915.85
Organism:
Human
Description:
O00299
Residue:
241
Sequence:
MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK
  
Inhibitor
Name:
BDBM525314
Synonyms:
US11173137, Compound MCFA
Type:
Small organic molecule
Emp. Form.:
C15H12Cl2NO2
Mol. Mass.:
309.168
SMILES:
Cc1ccc(Cl)c(Nc2ccccc2CC([O-])=O)c1Cl
Structure:
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