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Target
Probable G-protein coupled receptor 139
Ligand
BDBM263453
Substrate
n/a
Meas. Tech.
Radioligand Assay
Ki
58±n/a nM
Citation
 Hitchcock, S; Lam, B; Monenschein, H; Reichard, H 4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139 US Patent  US11173161 Publication Date 11/16/2021 
Target
Name:
Probable G-protein coupled receptor 139
Synonyms:
G(q)-coupled orphan receptor GPRg1 | G-protein coupled receptor 139 | G-protein-coupled receptor PGR3 | GP139_HUMAN | GPR139 | GPRG1 | GPRG1 | PGR3 | Probable G-protein coupled receptor 139
Type:
PROTEIN
Mol. Mass.:
40700.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109920
Residue:
353
Sequence:
MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATLKAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSP
  
Inhibitor
Name:
BDBM263453
Synonyms:
(s)-2-(6-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-p-tolylethyl)acetamide | US10561662, Example 18 | US11173161, EX 18 | US9556130, test 18
Type:
Small organic molecule
Emp. Form.:
C19H20N4O3
Mol. Mass.:
352.3871
SMILES:
COc1ccc2nnn(CC(=O)N[C@@H](C)c3ccc(C)cc3)c(=O)c2c1 |r|
Structure:
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