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Target
Luciferin 4-monooxygenase
Ligand
BDBM526431
Substrate
n/a
Meas. Tech.
YAP Reporter Assay
IC50
<100±n/a nM
Citation
 Konradi, AW; Lin, TT Non-fused tricyclic compounds US Patent  US11186554 Publication Date 11/30/2021 
Target
Name:
Luciferin 4-monooxygenase
Synonyms:
LUCI_LUCMI | Luciferase
Type:
Protein
Mol. Mass.:
60495.67
Organism:
Southern Russian firefly
Description:
Q26304
Residue:
548
Sequence:
MEMEKEENVVYGPLPFYPIEEGSAGIQLHKYMHQYAKLGAIAFSNALTGVDISYQEYFDITCRLAEAMKNFGMKPEEHIALCSENCEEFFIPVLAGLYIGVAVAPTNEIYTLRELNHSLGIAQPTIVFSSRKGLPKVLEVQKTVTCIKKIVILDSKVNFGGHDCMETFIKKHVELGFQPSSFVPIDVKNRKQHVALLMNSSGSTGLPKGVRITHEGAVTRFSHAKDPIYGNQVSPGTAILTVVPFHHGFGMFTTLGYFACGYRVVMLTKFDEELFLRTLQDYKCTSVILVPTLFAILNKSELIDKFDLSNLTEIASGGAPLAKEVGEAVARRFNLPGVRQGYGLTETTSAFIITPEGDDKPGASGKVVPLFKVKVIDLDTKKTLGVNRRGEICVKGPSLMLGYSNNPEATRETIDEEGWLHTGDIGYYDEDEHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPDAGELPGAVVVMEKGKTMTEKEIVDYVNSQVVNHKRLRGGVRFVDEVPKGLTGKIDAKVIREILKKPQAKM
  
Inhibitor
Name:
BDBM526431
Synonyms:
2-(2-(1-aminopropan-2-yl)-2H-tetrazol-5-yl)-N- (4-(trifluoromethyl)phenyl)aniline | US11186554, Compound 218
Type:
Small organic molecule
Emp. Form.:
C17H17F3N6
Mol. Mass.:
362.3523
SMILES:
CC(CN)n1nnc(n1)-c1ccccc1Nc1ccc(cc1)C(F)(F)F
Structure:
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