Reaction Details Report a problem with these data
Target
Histone deacetylase 11
Ligand
BDBM531084
Substrate
n/a
Meas. Tech.
IC50 Assay
IC50
3600±n/a nM
Citation
 Hooker, J; Wang, C; Strebl-Bantillo, MG HDAC6 inhibitors and imaging agents US Patent  US11207431 Publication Date 12/28/2021 
Target
Name:
Histone deacetylase 11
Synonyms:
HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11
Type:
Chromatin regulator; hydrolase; repressor
Mol. Mass.:
39187.66
Organism:
Homo sapiens (Human)
Description:
Q96DB2
Residue:
347
Sequence:
MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
  
Inhibitor
Name:
BDBM531084
Synonyms:
US11207431, Example C
Type:
Small organic molecule
Emp. Form.:
C16H22N4O2
Mol. Mass.:
302.3715
SMILES:
CN(c1ncc(cn1)C(=O)NO)C12CC3CC(CC(C3)C1)C2 |TLB:21:12:19:15.16.17,1:12:15:18.19.17,THB:21:16:19:20.13.12,20:18:15:21.13.12,20:12:15:18.19.17|
Structure:
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