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Target
Galectin-3
Ligand
BDBM541740
Substrate
n/a
Meas. Tech.
Biological Assay
IC50
15.0±n/a nM
Citation
 Jalagam, PR; Nair, SK; Panda, M; Sarabu, R; Swidorski, J; Beno, BR; Regueiro-Ren, A Small molecule inhibitors of galectin-3 US Patent  US11267811 Publication Date 3/8/2022 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM541740
Synonyms:
US11267811, Example A70
Type:
Small organic molecule
Emp. Form.:
C28H24FN7O4S
Mol. Mass.:
573.598
SMILES:
Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c3ccccc3c2)n(n1)-c1ccc2ncsc2c1 |r|
Structure:
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