Reaction Details Report a problem with these data
Target
Histone acetyltransferase KAT7
Ligand
BDBM580680
Substrate
n/a
Meas. Tech.
Kat7 Assay
Ki
0.000±n/a nM
Citation
 Bozikis, YE; Camerino, MA; Kung, P; Stupple, PA; Sutton, SC Benzisoxazole sulfonamide derivatives US Patent  US11492346 Publication Date 11/8/2022 
Target
Name:
Histone acetyltransferase KAT7
Synonyms:
2.3.1.48 | HBO1 | HBOa | Histone acetyltransferase KAT7 | Histone acetyltransferase binding to ORC1 | KAT7 | KAT7_HUMAN | Lysine acetyltransferase 7 | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2 | MYST-2 | MYST2 | Synonyms=HBO1
Type:
PROTEIN
Mol. Mass.:
70665.79
Organism:
Homo sapiens
Description:
ChEMBL_116753
Residue:
611
Sequence:
MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
  
Inhibitor
Name:
BDBM580680
Synonyms:
US11492346, Example 20
Type:
Small organic molecule
Emp. Form.:
C23H24N4O5S
Mol. Mass.:
468.525
SMILES:
COc1cc2CCCCc2cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12
Structure:
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